Structure of PDB 8it0 Chain E Binding Site BS02

Receptor Information
>8it0 Chain E (length=465) Species: 1393122 (Thermoflavifilum thermophilum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKELIYIEEPSILFAHGQKCTDPRDGLALFGPLNQIYGIKSGVVGTQKGL
QIFKSYLDKIQKPIYNHNNITRPMFPGFEAVFGCKWESQNIVFKEITDEE
IRRYLFNASTHKRTYDLVTLFNDKIITANKNDEERVDVWFVIVPEEIYKY
CRPNSVLYNYDAQFHDQLKARLLEHTIPTQILRESTLAWRDFKNTFGAPI
RDFSKIEGHLAWTISTAAYYKAGGKPWKLGDIRPGVCYLGLVYKKIEKSK
NPQNACCAAQMFLDNGDGTVFKGEVGPWYNPEKGEYHLKPKEAKALLTQA
LESYKEQNKSYPKEVFIHARTRFNDEEWNAFNEVTPKNTNLVGVTITKSK
PLKLYKTEGAFPIMRGNAYIVDEKKAFLWTLGFVPKLQSTLSMEVPNPIF
IEINKGEAEIQQVLKDILALTKLNYNACIYADGEPVTLRFANKIGEILTA
STEIKTPPLAFKYYI
Ligand information
>8it0 Chain G (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ugagguaguagguuguauagu
.....................
Receptor-Ligand Complex Structure
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PDB8it0 Nucleic acid-triggered NADase activation of a short prokaryotic Argonaute.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		E324 K325 L423 N439
Binding residue
(residue number reindexed from 1)		E282 K283 L381 N397
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding

View graph for
Molecular Function
External links
PDB RCSB:8it0, PDBe:8it0, PDBj:8it0
PDBsum8it0
PubMed37783228
UniProtA0A1I7NFD7

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