Structure of PDB 8h7a Chain E Binding Site BS02
Receptor Information
>8h7a Chain E (length=77) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
VKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQL
ELSVKDGTILKVSNKGLNSYKDPDNPG
Ligand information
>8h7a Chain H (length=13) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ggtccgacggacc
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
8h7a
The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.
Resolution
1.92 Å
Binding residue
(original residue number in PDB)
K24 Q25 R26
Binding residue
(residue number reindexed from 1)
K23 Q24 R25
Enzymatic activity
Enzyme Commision number
2.3.1.48
: histone acetyltransferase.
Gene Ontology
Molecular Function
GO:0003677
DNA binding
View graph for
Molecular Function
External links
PDB
RCSB:8h7a
,
PDBe:8h7a
,
PDBj:8h7a
PDBsum
8h7a
PubMed
36537216
UniProt
Q92794
|KAT6A_HUMAN Histone acetyltransferase KAT6A (Gene Name=KAT6A)
[
Back to BioLiP
]