Structure of PDB 8g8b Chain E Binding Site BS02

Receptor Information
>8g8b Chain E (length=107) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQ
DFKTDLRFQSSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQL
ARRIRGE
Ligand information
>8g8b Chain J (length=168) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
catatgctaatgtgtgcatgtgtgtgactatgtgcgcatgcatgtgcatg
tgtgtgcatatacgtgtgtgcatgcatgtgcatatatgtgtgcacgtgtg
tgtgcatgtgtgtgtatgtgtatatattaacctgtgtgcattgtgtgcat
atattagcatgtgtgcat
Receptor-Ligand Complex Structure
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PDB8g8b Histone modifications regulate pioneer transcription factor cooperativity.
Resolution4.3 Å
Binding residue
(original residue number in PDB)		K36 H39 Y41 R42 T45 R72 R83 F84 Q85 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)		K10 H13 Y15 R16 T19 R46 R57 F58 Q59 R90 V91 T92 M94
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8g8b, PDBe:8g8b, PDBj:8g8b
PDBsum8g8b
PubMed37225990
UniProtP84233|H32_XENLA Histone H3.2

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