Structure of PDB 8g86 Chain E Binding Site BS02

Receptor Information
>8g86 Chain E (length=96) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>8g86 Chain J (length=145) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tgtgactatgtgcgcatgcatgtgcatgtgtgtgcatatacgtgtgtgca
tgcatgtgcatatatgtgtgcacgtgtgtgtgcatgtgtgtgtatgtgta
tatattaacctgtgtgcattgtgtgcatatattagcatgtgtgca
Receptor-Ligand Complex Structure
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PDB8g86 Histone modifications regulate pioneer transcription factor cooperativity.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y41 R42 T45 R63 R72 R83 F84 R116 V117 T118 M120
Binding residue
(residue number reindexed from 1)		Y4 R5 T8 R26 R35 R46 F47 R79 V80 T81 M83
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8g86, PDBe:8g86, PDBj:8g86
PDBsum8g86
PubMed37225990
UniProtP84233|H32_XENLA Histone H3.2

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