Structure of PDB 8g57 Chain E Binding Site BS02

Receptor Information
>8g57 Chain E (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQ
SSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
Ligand information
>8g57 Chain J (length=150) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctag
caccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagg
ggattactccctagtctccaggcacgtgtcagatatatacatcctgtgca
Receptor-Ligand Complex Structure
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PDB8g57 Cryo-EM structure of the human Sirtuin 6-nucleosome complex.
Resolution3.07 Å
Binding residue
(original residue number in PDB)
R40 V46 K64 L65
Binding residue
(residue number reindexed from 1)
R5 V11 K29 L30
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8g57, PDBe:8g57, PDBj:8g57
PDBsum8g57
PubMed37058572
UniProtP84233|H32_XENLA Histone H3.2

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