Structure of PDB 7zke Chain E Binding Site BS02

Receptor Information
>7zke Chain E (length=1623) Species: 209285 (Thermochaetoides thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATRLDRLVTILETGSTRLIRDTAVNQLADWQKQHPEELFNLLSRVVPYLR
HKDWETRTTAAKAIGKIIENAPLYDPNANFFRLESLDVATIVKYGRPLLR
GGPVDYNLAALDPQKRLAHLKKTLNGRLGLLGRVFEDEEMPVEEIEADDG
AEWPFERLCEFLKVDLFDPQWETRHGAAMGLREVIRVHGAGAGRRRGKTR
KENNDLNRQWLDDLAYRLLCVLMLDKFTDYSSDTSVAPIRETVGQTLGAV
LRHISVESVHAIYRLLYCMVTQEDLPSEQNMWAVCHGGMVGLRYVVAVRK
DLLLQDGDMIDGVVRCVMQGLGDIDDDVRSVSAATLIPMAKEFVMMRRSA
LDSLINIVWESLSNLGDDLSASTGKIMDLLATLCSFPEVLEAMKVSASQD
EERSFTLLVPRLYPFLRHTITSVRLAVLKALMTFANLGGETSQGWLNGRI
LRLIFQNIIVERDQDTLNMSLELWTTLVRRLAARDPAILADEFEAHAEPM
MQLALHPIGVPRHPIPMNPALFQKPSGGHDVDGHMIQGEVDLVGVDVLIR
SRISAAKAMGLIMSFIPTPRLASYDTAVLQALSSPYASTQLAAAMVIDEY
AKNCSTPEVASRFIEPLQKIIDLERPSHYRDLVTYVQRVRSASQQLINLF
RDHGKVSQGKLPTLAVVVQGEPEAGPGAFSIANAEKVVNEDFERLKRLMA
PGQRLIALPQLNEAREQTVEVIEEAKAAKEARDARIKAAAACALVAMKVL
PKKPSPLIKAIMDSIKTEENQELQSRSAATIARLVQLFTESGRRGPAEKV
VANLVKFSCVEVAETPEFPIHAHKTNVILSMQKAVKYAREAKAARITRRG
AKEALEILSKNFGAELLERVPTLRTFMEEPLVRAFSGDLPPEARDPENAF
GQEIVDAMSVIRTMTPTLHPALHPFVMQQVPLVIKALRSDLSVFRYMAAK
CMATICSVITVDGMTALVEKVLPSINNPLDLSFRQGAIEVIYHLIAVMGD
AILPYVIFLIVPVLGRMSDSDNQIRLIATTSFATLVKLVPLEAGIPDPPG
LSEELLKGRDRERTFIAQLLDPKKIEPFKIPVAIKAELRSYQQEGVNWLA
FLNKYHLHGILCDDMGLGKTLQTICIVASDHHQRAEEFARTGAPEVRKLP
SLIICPPTLSGHWQQEIKTYAPFLTVTAYVGSPAERRAMKDSLDKTDIVI
TSYDVCRNDIDVIEKYNWNYCVLDEGHLIKNPKAKITLAVKRLTSNHRLI
LTGTPIQNNVLELWSLFDFLMPGFLGAEKVFLDRFAKPIANSRYSKASSK
EQEAGALAIEALHKQVLPFLLRRLKEEVLNDLPPKILQNYYCDLSDLQRK
LFEDFTKREGKKITETAGRDDKEAKQHIFQALQYMRKLCNSPALVMKPGH
KAYEDTQKYLAKHGTTLEDPIHAPKLGALRDLLVDCGIGVEGTPIKPHRA
LIFCQMKEMLDMVQNTVLKQMLPSVSYLRLDGSVEANKRQDIVNKFNSDP
SYDVLLLTTSVGGLGLNLTGADTVIFVEHDWNPQKDLQAMDRAHRIGQKK
VVNVYRIITRGTLEEKILSLQRFKIDVDMVDIETGDVRRPGKKAAWLEGL
GELWDNAQYEESFDLDGFLKTMQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB7zke Structural basis for TBP displacement from TATA box DNA by the Swi2/Snf2 ATPase Mot1.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		P1392 R1395 D1413 N1417 Q1589 M1673
Binding residue
(residue number reindexed from 1)		P1183 R1186 D1204 N1208 Q1380 M1456
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0017025 TBP-class protein binding
GO:0140658 ATP-dependent chromatin remodeler activity
Biological Process
GO:0006338 chromatin remodeling
Cellular Component
GO:0005634 nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7zke, PDBe:7zke, PDBj:7zke
PDBsum7zke
PubMed37106137
UniProtG0S6C0

[Back to BioLiP]