Structure of PDB 7zjw Chain E Binding Site BS02

Receptor Information
>7zjw Chain E (length=519) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GRRVNVNVGVLGHIDSGKTALARALSTLDLGFSCFSVPLPARLRSSLPGE
PLLQVTLVDCPGHASLIRTIIGGAQIIDLMMLVIDVTKGMQTQSAECLVI
GQIACQKLVVVLNKIDLLPEGKRQAAIDKMTKKMQKTLENTKFRGAPIIP
VAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRDPSGPFLMSVDHCFS
IKGQGTVMTGTILSGSISLGDSVEIPALKVVKKVKSMQMFHMPITSAMQG
DRLGICVTQFDPKLLERGLVCAPESLHTVHAALISVEKIPYFRGPLQTKA
KFHITVGHETVMGRLMFFSPAPDNFDQEPILDSFNFSQEYLFQEQYLSKD
HCPREQWALVEFEKPVTCPRLCLVIGSRLDADIHTNTCRLAFHGILLHGL
EDRNYADSFLPRLKVYKLKHKHGLVERAMDDYSVIGRSLFKKETNIQLFV
GLKVHLSTGELGIIDSAFGQSGKFKIHIPGGLSPESKKILTPASEPSQHV
VLSLTFKRYVFDTHKRMVQ
Ligand information
>7zjw Chain S (length=46) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caugacggucugccugaaaaccagcccgcugguggggcagucccga
......<<.<<........<<<<<....>>>>>.....>>.>>...
Receptor-Ligand Complex Structure
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PDB7zjw Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R491 F522 Q524 K527
Binding residue
(residue number reindexed from 1)		R437 F468 Q470 K473
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0035368 selenocysteine insertion sequence binding
GO:0043021 ribonucleoprotein complex binding
Biological Process
GO:0001514 selenocysteine incorporation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7zjw, PDBe:7zjw, PDBj:7zjw
PDBsum7zjw
PubMed35709277
UniProtP57772|SELB_HUMAN Selenocysteine-specific elongation factor (Gene Name=EEFSEC)

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