Structure of PDB 7w1e Chain E Binding Site BS02

Receptor Information
>7w1e Chain E (length=644) Species: 1194091 (Klebsiella phage NTUH-K2044-K1-1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APERVFSDLASMVAYPNFQVQDKITLLGSAGGDFTFTTTASVVDNGTVFA
VPGGYLLRKFVGPAYSSWFSNWTGIVTFMSAPNRHLVVDTVLQATSVLNI
KSNSTLEFTDTGRILPDAAVARQVLNITGSAPSVFVPLAADAAAGSKVIT
VAAGALSAVKGTYLYLRSNKLCDGGPNTYGVKISQIRKVVGVSTSGGVTS
IRLDKTLHYNYYLSDAAEVGIPTMVENVTLVSPYINEFGYDDLNRFFTIG
ISANFAADLHIQDGVIIGNKRPGASDIEGRSAIKFNNCVDSTVKGTCFYN
IGWYGVEVLGCSEDTEVHDIHAMDVRHAISLNWQSTADGDKWGEPIEFLG
VNCEAYSTTQAGFDTHDIGKRVKFVRCVSYDSAAAGFQARTNGVEYLNCR
AYRAAMDGFASNTGVAFPIYRECLAYDNVRSGFNCSYGGGYVYDCEAHGS
QNGVRINGGRVKGGRYTRNSSSHIFVTKDVAETAQTSLEIDGVSMRYDGT
GRAVYFHGTVGIDPTLVSMSNNDMTGHGLFWALLSGYTVQPTPPRMSRNL
LDDTGIRGVATLVAGEATVNARVRGNFGSVANSFKWVSEVKLTRLTFPSS
AGALTVTSVAQNQDVPTPNPDLNSFVIRSSNAADVSQVAWEVYL
Ligand information
Ligand IDBGC
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6-/m1/s1
InChIKeyWQZGKKKJIJFFOK-VFUOTHLCSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.370OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O
CACTVS 3.370OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
OpenEye OEToolkits 1.7.6C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O)O)O)O)O
ACDLabs 12.01OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namebeta-D-glucopyranose;
beta-D-glucose;
D-glucose;
glucose
ChEMBLCHEMBL1614854
DrugBankDB02379
ZINCZINC000003833800
PDB chain7w1e Chain N Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7w1e Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use.
Resolution1.46 Å
Binding residue
(original residue number in PDB)		Y186 E285 Y311 N339 W340 H373
Binding residue
(residue number reindexed from 1)		Y179 E278 Y304 N332 W333 H366
Annotation score4
Enzymatic activity
Enzyme Commision number 4.-.-.-
Gene Ontology
Biological Process
GO:0046718 symbiont entry into host cell
GO:0098671 adhesion receptor-mediated virion attachment to host cell
GO:0098994 symbiont entry into host cell via disruption of host cell envelope
GO:0098996 symbiont entry into host cell via disruption of host cell glycocalyx
Cellular Component
GO:0098015 virus tail

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w1e, PDBe:7w1e, PDBj:7w1e
PDBsum7w1e
PubMed35130876
UniProtA0A068Q5Q5|DEPOL_BPKNT Depolymerase, capsule K1-specific (Gene Name=ORF34)

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