Structure of PDB 7r6v Chain E Binding Site BS02

Receptor Information

>7r6v Chain E (length=289) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AVLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADR
KHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFY
LSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGK
KIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQ
PQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTL
YLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYE

Ligand information

>7r6v Chain B (length=10) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gcacgtcaga

Receptor-Ligand Complex Structure

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Structure summary

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PDB	7r6v Human EXOG possesses strong AP hydrolysis activity
Resolution	2.16 Å
Binding residue (original residue number in PDB)	K113 S172 G257 F258 F304 L311 K315
Binding residue (residue number reindexed from 1)	K54 S113 G198 F199 F245 L252 K256

Enzymatic activity

Enzyme Commision number

3.1.30.-

Gene Ontology

	Molecular Function
GO:0003676	nucleic acid binding
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

View graph for
Molecular Function

External links

PDB	RCSB:7r6v, PDBe:7r6v, PDBj:7r6v
PDBsum	7r6v
PubMed
UniProt	Q9Y2C4\|EXOG_HUMAN Nuclease EXOG, mitochondrial (Gene Name=EXOG)

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