Structure of PDB 7q3o Chain E Binding Site BS02

Receptor Information
>7q3o Chain E (length=60) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKDKYRVVYTDHQRLELEKEFHYSRYITIRRKSELAANLGLTERQVKIWF
QNRRAKERKV
Ligand information
Receptor-Ligand Complex Structure
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PDB7q3o Structure of CDX1 bound to hydroxymethylated DNA
Resolution2.78 Å
Binding residue
(original residue number in PDB)		Y189 R190 V192 K216 Q235 R238 R242
Binding residue
(residue number reindexed from 1)		Y5 R6 V8 K32 Q51 R54 R58
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7q3o, PDBe:7q3o, PDBj:7q3o
PDBsum7q3o
PubMed
UniProtP47902|CDX1_HUMAN Homeobox protein CDX-1 (Gene Name=CDX1)

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