Structure of PDB 7leu Chain E Binding Site BS02
Receptor Information
>7leu Chain E (length=423) Species:
10090
(Mus musculus) [
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NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYFS
Ligand information
>7leu Chain C (length=6) Species:
9606
(Homo sapiens) [
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EEKRKR
Receptor-Ligand Complex Structure
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PDB
7leu
Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Resolution
2.82 Å
Binding residue
(original residue number in PDB)
G281 N283 R315 N319 V321 T322 G323 T328 E354 W357 N361 E396 W399
Binding residue
(residue number reindexed from 1)
G207 N209 R241 N245 V247 T248 G249 T254 E280 W283 N287 E322 W325
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7leu
,
PDBe:7leu
,
PDBj:7leu
PDBsum
7leu
PubMed
35260573
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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