Structure of PDB 7let Chain E Binding Site BS02
Receptor Information
>7let Chain E (length=423) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYFS
Ligand information
>7let Chain C (length=6) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
EEKRKR
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
7let
Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
G281 N283 R315 N319 V321 T322 G323 T328 E354 W357 N361 A364 E396 W399 S406 G407
Binding residue
(residue number reindexed from 1)
G207 N209 R241 N245 V247 T248 G249 T254 E280 W283 N287 A290 E322 W325 S332 G333
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:7let
,
PDBe:7let
,
PDBj:7let
PDBsum
7let
PubMed
35260573
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
[
Back to BioLiP
]
