Structure of PDB 7f7i Chain E Binding Site BS02

Receptor Information
>7f7i Chain E (length=182) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYH
FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVS
ANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLE
QEFTECFSAIVEGDSFEEIYHKVKRVIEDLSG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7f7i Entropy of stapled peptide inhibitors in free state is the major contributor to the improvement of binding affinity with the GK domain.
Resolution2.595 Å
Binding residue
(original residue number in PDB)
Q603 S606
Binding residue
(residue number reindexed from 1)
Q72 S75
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:7f7i, PDBe:7f7i, PDBj:7f7i
PDBsum7f7i
PubMed34458841
UniProtP31016|DLG4_RAT Disks large homolog 4 (Gene Name=Dlg4)

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