Structure of PDB 7e3w Chain E Binding Site BS02

Receptor Information
>7e3w Chain E (length=231) Species: 1280 (Staphylococcus aureus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMMKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTH
GHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANF
DFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLF
SDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDT
FPLIEQDPQQFKDAVNVGDVQILKPGESVQF
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain7e3w Chain E Residue 302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB7e3w Metallo beta-lactamase fold protein
Resolution1.55 Å
Binding residue
(original residue number in PDB)		D52 H53 D144 H195
Binding residue
(residue number reindexed from 1)		D54 H55 D146 H197
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:7e3w, PDBe:7e3w, PDBj:7e3w
PDBsum7e3w
PubMed33950015
UniProtQ2FXM0|Y1815_STAA8 UPF0173 metal-dependent hydrolase SAOUHSC_01815 (Gene Name=SAOUHSC_01815)

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