Structure of PDB 7crr Chain E Binding Site BS02

Receptor Information
>7crr Chain E (length=98) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVKALQEASEAYLVGLFEDTNLCGIHAKRVTIKPKDIQLARRIRGER
Ligand information
>7crr Chain K (length=168) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ccggcactggaacaggatgtatatatctgacacgtgcctggagactaggg
agtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgttt
aagcggtgctagagctgtctacgaccaattgagcggcctcggcaccggga
ttctccaggggatcgggc
Receptor-Ligand Complex Structure
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PDB7crr Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Resolution3.48 Å
Binding residue
(original residue number in PDB)
Y41 V46 R49 K64 L65 P66 R69
Binding residue
(residue number reindexed from 1)
Y5 V10 R13 K28 L29 P30 R33
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus

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Molecular Function

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Cellular Component
External links
PDB RCSB:7crr, PDBe:7crr, PDBj:7crr
PDBsum7crr
PubMed33361816
UniProtQ92133

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