Structure of PDB 7by0 Chain E Binding Site BS02

Receptor Information
>7by0 Chain E (length=103) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPHRYRPGTVALREIRRYQKSTELLIRRQPFARVVREICLLFTRGVDYRW
QAMALLALQEAAEAFLVHLLEDAYLCSLHARRVTLYPKDLQLARRLRGLQ
GEG
Ligand information
>7by0 Chain J (length=143) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
tcgatgtatatatctgacacgtgcctggagactagggagtaatccccttg
gcggttaaaacgcgggggacagcgcgtacgtgcgtttaagcggtgctaga
gctgtctacgaccaattgagcggcctcggcaccgggattctga
Receptor-Ligand Complex Structure
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PDB7by0 Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		H40 Y42 R43 R64 R73 R86 W87 A89 R119 V120 T121 Y123
Binding residue
(residue number reindexed from 1)		H3 Y5 R6 R27 R36 R49 W50 A52 R82 V83 T84 Y86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7by0, PDBe:7by0, PDBj:7by0
PDBsum7by0
PubMed33463726
UniProtP84229|H32_CHICK Histone H3.2 (Gene Name=H3-I);
Q6XXM1

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