Structure of PDB 6zfm Chain E Binding Site BS02

Receptor Information
>6zfm Chain E (length=65) Species: 8649 (Naja kaouthia) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IRCFITPDISKDCPNGHVCYTKTWCDAFCSIRGKRVDLGCAATCPTVKTG
VDIQCCSTDNCNPFP
Ligand information
Ligand IDQJE
InChIInChI=1S/C15H33NO7/c16-2-5-19-7-9-21-11-13-23-15-14-22-12-10-20-8-6-18-4-1-3-17/h17H,1-16H2
InChIKeyZSCFOXFWAAWAJH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7C(CO)COCCOCCOCCOCCOCCOCCN
CACTVS 3.385NCCOCCOCCOCCOCCOCCOCCCO
FormulaC15 H33 N O7
Name3-[2-[2-[2-[2-[2-(2-azanylethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propan-1-ol
ChEMBL
DrugBank
ZINC
PDB chain6zfm Chain F Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6zfm Peptide Inhibitors of the alpha-Cobratoxin-Nicotinic Acetylcholine Receptor Interaction.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		R36 V37
Binding residue
(residue number reindexed from 1)		R35 V36
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0030550 acetylcholine receptor inhibitor activity
GO:0090729 toxin activity
GO:0099106 ion channel regulator activity
Biological Process
GO:0035821 modulation of process of another organism
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6zfm, PDBe:6zfm, PDBj:6zfm
PDBsum6zfm
PubMed33143415
UniProtP01391|3L21_NAJKA Alpha-cobratoxin

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