Structure of PDB 6sic Chain E Binding Site BS02

Receptor Information
>6sic Chain E (length=285) Species: 930945 (Sulfolobus islandicus REY15A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PYYAFAEPFFIHAITHLHVGSGSSVEEEIALPFQRDELGYPTIYASSLKG
AIKSFLLKEFPDKRDVIYKVLGEDENPEEASLGTFLDAILFAIPSRIIEI
DSAKPYVWVYVTTYELLKKVKLYLDSISQLSNASFSNLKNKIDTILAKEG
KNITLDSDLKSAILNEDFYVELEALNNKIPSIINAGVPLLVLEDSIGREV
INRSLIRVRRIRIDRDKKVVETGGLWSEEYVPMKTIFFSVLLGKESKESA
IFASCILRNLRYVILGGKETIGKGIVELRWVKDVI
Ligand information
>6sic Chain V (length=48) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auugaaaguucaaagcuuagauacccuggagggaaaccagacuuaaca
................................................
Receptor-Ligand Complex Structure
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PDB6sic Structures of the Cmr-beta Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas.
Resolution3.52 Å
Binding residue
(original residue number in PDB)
V20 G21 G23 S47 S48 K50 G51 A52 K54 E74 D75 A81 S82 R211 I212 R213 I214 R216 K219 W227 L266 G267 G268 K269 E270 T271
Binding residue
(residue number reindexed from 1)
V19 G20 G22 S46 S47 K49 G50 A51 K53 E73 D74 A80 S81 R210 I211 R212 I213 R215 K218 W226 L265 G266 G267 K268 E269 T270
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Biological Process
External links
PDB RCSB:6sic, PDBe:6sic, PDBj:6sic
PDBsum6sic
PubMed32730741
UniProtF0NDX6

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