Structure of PDB 6pwe Chain E Binding Site BS02

Receptor Information
>6pwe Chain E (length=96) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6pwe Chain J (length=147) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcgagaatcccggtgccgaggccgctcaattggtcgtagacagctctag
caccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgccaagg
ggattactccctagtctccaggcacgtgtcagatatatacatccgat
Receptor-Ligand Complex Structure
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PDB6pwe Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome.
Resolution3.95 Å
Binding residue
(original residue number in PDB)		R40 Y41 R42 T45 R72 R83 F84 R116 T118
Binding residue
(residue number reindexed from 1)		R3 Y4 R5 T8 R35 R46 F47 R79 T81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005700 polytene chromosome
GO:0035059 RCAF complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6pwe, PDBe:6pwe, PDBj:6pwe
PDBsum6pwe
PubMed31402386
UniProtP02299|H3_DROME Histone H3 (Gene Name=His3)

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