Structure of PDB 6cw3 Chain E Binding Site BS02

Receptor Information
>6cw3 Chain E (length=120) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSNKFHCDVCSADCTNRVRVSCAICPEYDLCVPCFSQGSYTGKHRPYHDY
RIIETNSYPILCPDWGADEELQLIKGAQTLGLGNWQDIADHIGSRGKEEV
KEHYLKYYLESKYYPIPDIT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6cw3 Chain E Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6cw3 Structural basis for activation of SAGA histone acetyltransferase Gcn5 by partner subunit Ada2.
Resolution1.98 Å
Binding residue
(original residue number in PDB)
C22 C25 H44 H48
Binding residue
(residue number reindexed from 1)
C22 C25 H44 H48
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:6cw3, PDBe:6cw3, PDBj:6cw3
PDBsum6cw3
PubMed30224453
UniProtQ02336|ADA2_YEAST Transcriptional adapter 2 (Gene Name=ADA2)

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