Structure of PDB 5xuz Chain E Binding Site BS02

Receptor Information
>5xuz Chain E (length=1208) Species: 1410628 (Lachnospiraceae bacterium ND2006) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMSKLEKFTNCYSLSKTLRFKAIPVGKTQENIDNKRLLVEDEKRAEDY
KGVKKLLDRYYLSFINDVLHSIKLKNLNNYISLFRKKTRTEKENKELENL
EINLRKEIAKAFKGNEGYKSLFKKDIIETILPEFLDDKDEIALVNSFNGF
TTAFTGFFDNRENMFSEEAKSTSIAFRCINENLTRYISNMDIFEKVDAIF
DKHEVQEIKEKILNSDYDVEDFFEGEFFNFVLTQEGIDVYNAIIGGFVTE
SGEKIKGLNEYINLYNQKTKQKLPKFKPLYKQVLSDRESLSFYGEGYTSD
EEVLEVFRNTLNKNSEIFSSIKKLEKLFKNFDEYSSAGIFVKNGPAISTI
SKDIFGEWNVIRDKWNAEYDDIHLVTEKYEDDRRKSFKKIGSFSLEQLQE
YADADLSVVEKLKEIIIQKVDEIYKVYGSSEKLFDADFVLEKSLKKNDAV
VAIMKDLLDSVKSFENYIKAFFGEGKETNRDESFYGDFVLAYDILLKVDH
IYDAIRNYVTQKPYSKDKFKLYFQNPQFMGGWDKDKETDYRATILRYGSK
YYLAIMDKKYAKCLQKIDKDDVNGNYEKINYKLLPGPNKMLPKVFFSKKW
MAYYNPSEDIQKIYKNGTFKKGDMFNLNDCHKLIDFFKDSISRYPKWSNA
YDFNFSETEKYKDIAGFYREVEEQGYKVSFESASKKEVDKLVEEGKLYMF
QIYNKDFSDKSHGTPNLHTMYFKLLFDENNHGQIRLSGGAELFMRRASLK
KEELVVHPANSPIANKNPDNPKKTTTLSYDVYKDKRFSEDQYELHIPIAI
NKCPKNIFKINTEVRVLLKHDDNPYVIGIDRGERNLLYIVVVDGKGNIVE
QYSLNEIINNFNGIRIKTDYHSLLDKKEKERFEARQNWTSIENIKELKAG
YISQVVHKICELVEKYDAVIALEDLNVKVEKQVYQKFEKMLIDKLNYMVD
KKSNPCATGGALKGYQITNKFESFKSMSTQNGFIFYIPAWLTSKIDPSTG
FVNLLKTKYTSIADSKKFISSFDRIMYVPEEDLFEFALDYKNFSRTDADY
IKKWKLYSYGNRIRIFDWEEVCLTSAYKELFNKYGINYQQGDIRALLCEQ
SDKAFYSSFMALMSLMLQMRNSITGRTDVDFLISPVKNSDGIFYDSRNYE
AQENAILPKNADANGAYNIARKVLWAIGQFKKAEDEKLDKVKIAISNKEW
LEYAQTSV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5xuz Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		N160 K167 S168 G242 V245 K251 N256 E257 N260 K272 S286 S288 Y290 K349 W355 N509 T512 Q513 K514 D535 K538 Y542 L585 P587 M592 S599 K600 K601 Y646 K648 W649 S739 G740 N895 I896 K897 K945 S982 F983 K984
Binding residue
(residue number reindexed from 1)		N163 K170 S171 G245 V248 K254 N259 E260 N263 K275 S289 S291 Y293 K352 W358 N507 T510 Q511 K512 D533 K536 Y540 L583 P585 M590 S597 K598 K599 Y644 K646 W647 S737 G738 N893 I894 K895 K936 S973 F974 K975
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5xuz, PDBe:5xuz, PDBj:5xuz
PDBsum5xuz
PubMed28781234
UniProtA0A182DWE3

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