Structure of PDB 5mog Chain E Binding Site BS02

Receptor Information
>5mog Chain E (length=466) Species: 39946 (Oryza sativa Indica Group) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDG
DWYETGLHIFFGAYPNIQNLFGELGINDRLQWKEHSMIFAMPNKPGEFSR
FDFPETLPAPLNGIWAILRNNEMLTWPEKVKFALGLLPAMVGGQAYVEAQ
DGFTVSEWMKKQGVPDRVNDEVFIAMSKALNFINPDELSMQCILIALNRF
LQEKHGSKMAFLDGNPPERLCMPIVDHVRSLGGEVRLNSRIQKIELNPDG
TVKHFALTDGTQITGDAYVFATPVDILKLLVPQEWKEISYFKKLEKLVGV
PVINVHIWFDRKLKNTYDHLLFSRSSLLSVYADMSVTCKEYYDPNRSMLE
LVFAPAEEWVGRSDTEIIEATMQELAKLFPDEIAADQSKAKILKYHVVKT
PRSVYKTIPDCEPCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLC
AQSVVEDYKMLSRRSL
Ligand information
Ligand IDNRF
InChIInChI=1S/C12H9ClF3N3O/c1-17-9-6-18-19(11(20)10(9)13)8-4-2-3-7(5-8)12(14,15)16/h2-6,17H,1H3
InChIKeyNVGOPFQZYCNLDU-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.6CNC1=C(C(=O)N(N=C1)c2cccc(c2)C(F)(F)F)Cl
CACTVS 3.385CNC1=C(Cl)C(=O)N(N=C1)c2cccc(c2)C(F)(F)F
FormulaC12 H9 Cl F3 N3 O
NameNorflurazon
ChEMBLCHEMBL1881194
DrugBank
ZINCZINC000000271610
PDB chain5mog Chain E Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5mog Structure of Phytoene Desaturase Provides Insights into Herbicide Binding and Reaction Mechanisms Involved in Carotene Desaturation.
Resolution2.77 Å
Binding residue
(original residue number in PDB)		F162 A280 L281 R300 F423 A539
Binding residue
(residue number reindexed from 1)		F61 A179 L180 R199 F322 A438
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.5: 15-cis-phytoene desaturase.
Gene Ontology
Molecular Function
GO:0016166 phytoene dehydrogenase activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0016117 carotenoid biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5mog, PDBe:5mog, PDBj:5mog
PDBsum5mog
PubMed28669634
UniProtA2XDA1|PDS_ORYSI 15-cis-phytoene desaturase, chloroplastic/chromoplastic (Gene Name=PDS1)

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