Structure of PDB 5jup Chain E Binding Site BS02

Receptor Information
>5jup Chain E (length=171) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSKITSSQVREHVKELLKYSNETKKRNFLETVELQVSICIFGDAFDVDRA
KSCGVDAMSVDDLKKLNKNKKLIKKLSKKYNAFIASEVLIKQVPRLLGPQ
LSKAGKFPTPVSHNDDLYGKVTDVRVEMEEDVLVNQILMSVNFFVSLLKK
NWQNVGSLVVKSSMGPAFRLY
Ligand information
>5jup Chain EC (length=198) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaacuccauguauugguuacccaucugcaucgaaaacucuccgaacacua
ggugcaguaaggcuuucauggagugguuugcuauuuagcguacguguacc
auaggcagccccaaaaacacguaggagaaagucccagucacuuugggcaa
aguagacagccgcgcuugcguggugggacuuaauuaaugccugcuaac
...<<<<<<<..............<<<<<<.......(((..........
.>>>>>>.........>>>>>>>.(((.<<<<....>>>>..<<<<.)))
...<<.....>>.....>>>>....)))..<<<<<.<<<<<<..(((((.
>>>.>>>.<<<<<<....>>>>>>>>>>>........)))))......
Receptor-Ligand Complex Structure
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PDB5jup Ensemble cryo-EM uncovers inchworm-like translocation of a viral IRES through the ribosome.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		I117 P121 S129 G132 F134
Binding residue
(residue number reindexed from 1)		I90 P94 S102 G105 F107
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0000055 ribosomal large subunit export from nucleus
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5jup, PDBe:5jup, PDBj:5jup
PDBsum5jup
PubMed27159452
UniProtP0CX43|RL1A_YEAST Large ribosomal subunit protein uL1A (Gene Name=RPL1A)

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