Structure of PDB 5cd1 Chain E Binding Site BS02

Receptor Information
>5cd1 Chain E (length=367) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HRIRDGDFVVLKREDVFKAVQVQRRKKVTFEKQWFYLDNVIGHSYGTAFE
VTSGGSLQPKKKEAGTDNRNIVDDGKSQKLTQDDIKALKDKGIKGEEIVQ
QLIENSTTFRDKTEFAQDKYIKKKKKKYEAIITVVKPSTRILSIMYYARE
PGKINHMRYDTLAQMLTLGNIRAGNKMIVMETCAGLVLGAMMERMGGFGS
IIQLYPGGGPVRAATACFGFPKSFLSGLYEFPLNKVDSLLHGTFSYIQEK
QRRQEEQRKRHLEAAALLSERNADGLIVASRFHPTPLLLSLLDFVAPSRP
FVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKLLM
SGGGGYLLSGFTVAMDN
Ligand information
>5cd1 Chain N (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcccggauagcucagucgguagagcaucagacuuuuaaucugagggucc
aggguucaagucccuguucgggcgcc
.<<<<<<<..<<<<........>>>>.<<<<<.<...>.>>>>>.....<
<<<<.......>>>>>>>>>>>>...
Receptor-Ligand Complex Structure
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PDB5cd1 Crystal Structure of the Human tRNA m(1)A58 Methyltransferase-tRNA3(Lys) Complex: Refolding of Substrate tRNA Allows Access to the Methylation Target.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y411 R415 N422 L423
Binding residue
(residue number reindexed from 1)		Y315 R319 N326 L327
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0031515 tRNA (m1A) methyltransferase complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5cd1, PDBe:5cd1, PDBj:5cd1
PDBsum5cd1
PubMed26470919
UniProtQ9UJA5|TRM6_HUMAN tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 (Gene Name=TRMT6)

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