Structure of PDB 4yig Chain E Binding Site BS02

Receptor Information
>4yig Chain E (length=220) Species: 10249 (Vaccinia virus Copenhagen) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPMNSVTVSHAPYTITYHDDWEPVMSQLVEFYNEVASWLLRDETSPIPDK
FFIQLKQPLRNKRVCVCGIDPYPKDGTGVPFESPNFTKKSIKEIASSISR
LTGVIDYKGYNLNIIDGVIPWNYYLSCKLGETKSHAIYWDKISKLLLQHI
TKHVSVLYCLGKTDFSNIRAKLESPVTTIVGYHPAARDRQFEKDRSFEII
NVLLELDNKVPINWAQGFIY
Ligand information
Receptor-Ligand Complex Structure
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PDB4yig Crystal Structure of the Vaccinia Virus Uracil-DNA Glycosylase in Complex with DNA.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R185 R187
Binding residue
(residue number reindexed from 1)		R187 R189
Enzymatic activity
Enzyme Commision number 3.2.2.27: uracil-DNA glycosylase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004844 uracil DNA N-glycosylase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
Biological Process
GO:0006281 DNA repair
GO:0039693 viral DNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:4yig, PDBe:4yig, PDBj:4yig
PDBsum4yig
PubMed26045555
UniProtP20536|UNG_VACCC Uracil-DNA glycosylase (Gene Name=OPG116)

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