Structure of PDB 4xgr Chain E Binding Site BS02

Receptor Information
>4xgr Chain E (length=128) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MMVIDTSALVAMLSDEPDAERFEAAVEADHIRLMSTASYLETALVIEARF
GEPGGRELDLWLHRAAVDLVAVHADQADAARAAYRTYGKAGLNYGDCFSY
GLAKISGQPLLFKGEDFQHTDIATVALP
Ligand information
>4xgr Chain F (length=24) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RDELAAIRHRCAALPVVDNRSAEA
Receptor-Ligand Complex Structure
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PDB4xgr Structural and functional studies of the Mycobacterium tuberculosis VapBC30 toxin-antitoxin system: implications for the design of novel antimicrobial peptides
Resolution2.7 Å
Binding residue
(original residue number in PDB)		M11 L12 D14 E22 E26 A47 R48 F49 P52 G53 E56 L59 W60
Binding residue
(residue number reindexed from 1)		M12 L13 D15 E23 E27 A48 R49 F50 P53 G54 E57 L60 W61
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004518 nuclease activity
GO:0004540 RNA nuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0045926 negative regulation of growth

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Molecular Function
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Biological Process
External links
PDB RCSB:4xgr, PDBe:4xgr, PDBj:4xgr
PDBsum4xgr
PubMed26150422
UniProtP9WF77|VPC30_MYCTU Ribonuclease VapC30 (Gene Name=vapC30)

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