Structure of PDB 4ol8 Chain E Binding Site BS02

Receptor Information
>4ol8 Chain E (length=381) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PVWLQQKYREIIRNDLPPRPVKHDIEIKPGARLPRLQPYHVTEKNEQEIN
KIVQKLLDNKFIVPSKSPCSSPVVLVPGTFRLCVDYRTLNKATISDPFPL
PRIDNLLSRIGNAQIFTTLDLHSGYHQIPMEPKDRYKTAFVTPSGKYEYT
VMPFGLVNAPSTFARYMADTFRDLRFVNVYLDDILIFSESPEEHWKHLDT
VLERLKNENLIVKKKKCKFASEETEFLGYSIGIQKIAPHKCAAIRDFPTP
KTVKQAQRFLGMINYYRRFIPNCSKIAQPITEKQDKAIDKLKSPVLVPFN
YRLTTDASKDGIGAVLEVGYFSKSLESAQGELELLGIIKALHHFRYMLHG
KHFTLRTNHIEPARRVQRWLDDLATYDFTLE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4ol8 Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.
Resolution3.1 Å
Binding residue
(original residue number in PDB)
Y211 D213 L258 K287 Q290 R291 G294 Y298
Binding residue
(residue number reindexed from 1)
Y180 D182 L227 K254 Q257 R258 G261 Y265
Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
3.4.23.-
External links
PDB RCSB:4ol8, PDBe:4ol8, PDBj:4ol8
PDBsum4ol8
PubMed24608367
UniProtQ99315|YG31B_YEAST Transposon Ty3-G Gag-Pol polyprotein (Gene Name=TY3B-G)

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