Structure of PDB 4gdf Chain E Binding Site BS02

Receptor Information
>4gdf Chain E (length=497) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEY
LMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMET
KCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADS
KNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTG
SADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDS
GKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNE
YSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLI
WYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gdf Mechanism of Origin DNA Recognition and Assembly of an Initiator-Helicase Complex by SV40 Large Tumor Antigen.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
N153 T155 H203 R204 A207 N210 Q267 V268 S269 W270 K271 K331 N332 K512 H513
Binding residue
(residue number reindexed from 1)
N23 T25 H73 R74 A77 N80 Q137 V138 S139 W140 K141 K201 N202 K382 H383
Enzymatic activity
Enzyme Commision number 3.6.4.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003688 DNA replication origin binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

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Molecular Function

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Biological Process
External links
PDB RCSB:4gdf, PDBe:4gdf, PDBj:4gdf
PDBsum4gdf
PubMed23545501
UniProtP03070|LT_SV40 Large T antigen

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