Structure of PDB 3mlp Chain E Binding Site BS02
Receptor Information
>3mlp Chain E (length=303) Species:
10090
(Mus musculus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
VLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIE
RTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMT
KQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDR
FFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVH
NNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQ
VIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRF
IYT
Ligand information
>3mlp Chain H (length=22) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
ctttattcccatgggaataaag
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3mlp
Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Resolution
2.8 Å
Binding residue
(original residue number in PDB)
G171 N174 N197 N201 A202 G203 N204 H235 N236 N237 H240
Binding residue
(residue number reindexed from 1)
G136 N139 N162 N166 A167 G168 N169 H200 N201 N202 H205
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:3mlp
,
PDBe:3mlp
,
PDBj:3mlp
PDBsum
3mlp
PubMed
20876732
UniProt
Q07802
|COE1_MOUSE Transcription factor COE1 (Gene Name=Ebf1)
[
Back to BioLiP
]