Structure of PDB 3mlp Chain E Binding Site BS02

Receptor Information
>3mlp Chain E (length=303) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VLDANTAAQSGVGLARAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIE
RTAFVGFVEKEKEANSEKTNNGIHYRLQLLYSNGIRTEQDFYVRLIDSMT
KQAIVYEGQDKNPEMCRVLLTHEIMCSRCCDKKSCGNRNETPSDPVIIDR
FFLKFFLKCNQNCLKNAGNPRDMRRFQVVVSTTVNVDGHVLAVSDNMFVH
NNSKHGRRARRLDPSEAATPCIKAISPSEGWTTGGATVIIIGDNFFDGLQ
VIFGTMLVWSELITPHAIRVQTPPRHIPGVVEVTLSYKSKQFCKGTPGRF
IYT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3mlp Structure of an Ebf1:DNA complex reveals unusual DNA recognition and structural homology with Rel proteins
Resolution2.8 Å
Binding residue
(original residue number in PDB)
G171 N174 N197 N201 A202 G203 N204 H235 N236 N237 H240
Binding residue
(residue number reindexed from 1)
G136 N139 N162 N166 A167 G168 N169 H200 N201 N202 H205
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:3mlp, PDBe:3mlp, PDBj:3mlp
PDBsum3mlp
PubMed20876732
UniProtQ07802|COE1_MOUSE Transcription factor COE1 (Gene Name=Ebf1)

[Back to BioLiP]