Structure of PDB 2xro Chain E Binding Site BS02

Receptor Information
>2xro Chain E (length=239) Species: 303 (Pseudomonas putida) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVIARAASIMRALGSHPHGLSLAAIAQLVGLPRSTVQRIINALEEEFLVE
ALGPAGGFRLGPALGQLINQAQTDILSLVKPYLRSLAEELDESVSLASLA
GDKIYVLDRIVSERELRVVFPIGINVPAAATAAGKVLLAALPDETLQAAL
GEQLPVLTSNTLGRKALVKQLSEVRQSGVASDLDEHIDGVSSFATLLDTY
LGYYSLAIVMPSSRASKQSDLIKKALLQSKLNIERAIGR
Ligand information
>2xro Chain Y (length=43) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gctgaatcgtaatgcggtagagtgtagcattatgtgatactct
Receptor-Ligand Complex Structure
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PDB2xro Crystal Structure of Ttgv in Complex with its DNA Operator Reveals a General Model for Cooperative DNA Binding of Tetrameric Gene Regulators.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		V16 R19 P46 S48 T49 R52
Binding residue
(residue number reindexed from 1)		V2 R5 P32 S34 T35 R38
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:2xro, PDBe:2xro, PDBj:2xro
PDBsum2xro
PubMed21078819
UniProtQ93PU6|TTGV_PSEPT HTH-type transcriptional regulator TtgV (Gene Name=ttgV)

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