Structure of PDB 2hn2 Chain E Binding Site BS02

Receptor Information
>2hn2 Chain E (length=331) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KKGLPPGTLVYTGKYREDFEIEVMNYSIEEFREFKTTDVESVLPFRDSST
PTWINITGIHRTDVVQRVGEFFGIHPLVLEDILNVHQRPKVEFFENYVFI
VLKMFTYDKNLHELESEQVSLILTKNCVLMFQEKIGDVFDPVRERIRYNR
GIIRKKRADYLLYSLIDALVDDYFVLLEKIDDEIDVLEEEVLERPEKETV
QRTHQLKRNLVELRKTIWPLREVLSSLYRDVPPLIEKETVPYFRDVYDHT
IQIADTVETFRDIVSGLLDVYLSSVSNKTNEVMKVLTIIATIFMPLTFIA
GIYGMNFGYPVVLAVMGVIAVIMVVYFKKKK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2hn2 Chain E Residue 6215 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2hn2 A structural basis for Mg(2+) homeostasis and the CorA translocation cycle.
Resolution3.7 Å
Binding residue
(original residue number in PDB)		D5175 D5179
Binding residue
(residue number reindexed from 1)		D167 D171
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0015087 cobalt ion transmembrane transporter activity
GO:0015095 magnesium ion transmembrane transporter activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0046873 metal ion transmembrane transporter activity
GO:0050897 cobalt ion binding
Biological Process
GO:0006811 monoatomic ion transport
GO:0006824 cobalt ion transport
GO:0015693 magnesium ion transport
GO:0030001 metal ion transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
GO:1903830 magnesium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2hn2, PDBe:2hn2, PDBj:2hn2
PDBsum2hn2
PubMed16902408
UniProtQ9WZ31|CORA_THEMA Cobalt/magnesium transport protein CorA (Gene Name=corA)

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