Structure of PDB 2dym Chain E Binding Site BS02

Receptor Information
>2dym Chain E (length=247) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHMNDIKQLLWNGELNVLVSIDPSFLMEIAVLRIRVPRETYLVNYMPLIW
NKEKYFWFEHNKTPIPWNYPVGVLFDCLASFENQVKDVLTFLRIHLVMGD
SLPPTIIPIASSKTQAEKFWFHQWKQVCFILNGSSKAIMSLSVNEARKFW
GSVITRNFQDFIEISNKISSSRPRHIPLIIQTSRTRISQPTISMTGVNPT
LKDIEGDILDVMVICQGIEIPWHMLLYDLYSKLRSFDGFLYITLVPI
Ligand information
>2dym Chain F (length=24) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SMDDLLIRRLTDRNDKEAHLNELF
Receptor-Ligand Complex Structure
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PDB2dym Structure of Atg5.Atg16, a complex essential for autophagy
Resolution2.2 Å
Binding residue
(original residue number in PDB)		I4 L7 L8 G11 L13 N14 V15 R36 R38 R41 S104 F105 D111 Q253 I255 E256 H260 M261 K269
Binding residue
(residue number reindexed from 1)		I6 L9 L10 G13 L15 N16 V17 R33 R35 R38 S80 F81 D87 Q216 I218 E219 H223 M224 K232
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008047 enzyme activator activity
GO:0016787 hydrolase activity
GO:0019776 Atg8-family ligase activity
GO:0140355 cargo receptor ligand activity
Biological Process
GO:0000045 autophagosome assembly
GO:0000422 autophagy of mitochondrion
GO:0000423 mitophagy
GO:0006914 autophagy
GO:0006995 cellular response to nitrogen starvation
GO:0015031 protein transport
GO:0016236 macroautophagy
GO:0032258 cytoplasm to vacuole targeting by the Cvt pathway
GO:0034727 piecemeal microautophagy of the nucleus
GO:0044804 nucleophagy
GO:0051365 cellular response to potassium ion starvation
Cellular Component
GO:0000407 phagophore assembly site
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005776 autophagosome
GO:0005829 cytosol
GO:0016020 membrane
GO:0034045 phagophore assembly site membrane
GO:0034274 Atg12-Atg5-Atg16 complex
GO:0044233 mitochondria-associated endoplasmic reticulum membrane contact site
GO:0061908 phagophore
GO:0120095 vacuole-isolation membrane contact site
GO:1990234 transferase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2dym, PDBe:2dym, PDBj:2dym
PDBsum2dym
PubMed17192262
UniProtQ12380|ATG5_YEAST Autophagy protein 5 (Gene Name=ATG5)

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