Structure of PDB 2c9f Chain E Binding Site BS02

Receptor Information
>2c9f Chain E (length=440) Species: 10515 (Human adenovirus 2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RNSIRYSELAPLFDTTRVYLVDNKSTDVASLNYQNDHSNFLTTVIQNNDY
SPGEASTQTINLDDRSHWGGDLKTILHTNMPNVNEFMFTNKFKARVMVSR
SLTKDKQVELKYEWVEFTLPEGNYSETMTIDLMNNAIVEHYLKVGRQNGV
LESDIGVKFDTRNFRLGFDPVTGLVMPGVYTNEAFHPDIILLPGCGVDFT
HSRLSNLLGIRKRQPFQEGFRITYDDLEGGNIPALLDVDAYQASLKKPVI
KPLTEDSKKRSYNLISNDSTFTQYRSWYLAYNYGDPQTGIRSWTLLCTPD
VTCGSEQVYWSLPDMMQDPVTFRSTSQISNFPVVGAELLPVHSKSFYNDQ
AVYSQLIRQFTSLTHVFNRFPENQILARPPAPTITTVSENVPALTDHGTL
PLRNSIGGVQRVTITDARRRTCPYVYKALGIVSPRVLSSR
Ligand information
Receptor-Ligand Complex Structure
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PDB2c9f Structure of the Dodecahedral Penton Particle from Human Adenovirus Type 3.
Resolution16.5 Å
Binding residue
(original residue number in PDB)
R197 E203 K385 T491 H492 R496 F497 P498
Binding residue
(residue number reindexed from 1)
R146 E152 K258 T364 H365 R369 F370 P371
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Biological Process
GO:0019062 virion attachment to host cell
GO:0046718 symbiont entry into host cell
GO:0075509 endocytosis involved in viral entry into host cell
GO:0075512 clathrin-dependent endocytosis of virus by host cell
Cellular Component
GO:0039623 T=25 icosahedral viral capsid
GO:0042025 host cell nucleus

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2c9f, PDBe:2c9f, PDBj:2c9f
PDBsum2c9f
PubMed16375921
UniProtP03276|CAPSP_ADE02 Penton protein (Gene Name=L2)

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