BioLiP

Receptor Information

>1tzn Chain E (length=552) Species: 191218 (Bacillus anthracis str. A2012) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TVPDRDNDGIPDSLEVEGYTVDVKNKRTFLSPWISNIHEKKGLTKYKSSP
EKWSTASDPYSDFEKVTGRIDKNVSPEARHPLVAAYPIVHVDMENIILSK
NEDSQTRTISKNTSTSRTHTSEVHGNAEVHASFFDIGGSVSAGFSNSNSS
TVAIDHSLSLAGERTWAETMGLNTADTARLNANIRYVNTGTAPIYNVLPT
TSLVLGKNQTLATIKAKENQLSQILAPNNYYPSKNLAPIALNAQSSTPIT
MNYNQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQ
IQETTARIIFNGKDLNLVERRIAAVNPSDPLETTKPDMTLKEALKIAFGF
NEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNATNIYTVLDKIKL
NAKMNILIRDKRFHYDRNNIAVGADESVVKEAHREVINSSTEGLLLNIDK
DIRKILSGYIVEIEDTEGLKEVINDRYDMLNISSLRQDGKTFIDFKKYND
KLPLYISNPNYKVNVYAVTKENTIINPSENGDTSTNGIKKILIFSKKGYE
IG

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1tzn Chain E Residue 737 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	1tzn Structure of heptameric protective antigen bound to an anthrax toxin receptor: A role for receptor in pH-dependent pore formation
Resolution	4.3 Å
Binding residue (original residue number in PDB)	D179 D181 E188 S222 P223 K225 D235
Binding residue (residue number reindexed from 1)	D6 D8 E15 S49 P50 K52 D62
Annotation score	4

Enzyme Commision number

	Biological Process
GO:0051260	protein homooligomerization

	Cellular Component
GO:0005576	extracellular region

PDB	RCSB:1tzn, PDBe:1tzn, PDBj:1tzn
PDBsum	1tzn
PubMed	15326297
UniProt	P13423\|PAG_BACAN Protective antigen (Gene Name=pagA)

[Back to BioLiP]

Structure of PDB 1tzn Chain E Binding Site BS02