Structure of PDB 1q3v Chain E Binding Site BS02
Receptor Information
>1q3v Chain E (length=321) Species:
10678
(Punavirus P1) [
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DEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPED
VRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRRI
RKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYNT
LLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTKL
VERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHR
LIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNI
VMNYIRNLDSETGAMVRLLED
Ligand information
>1q3v Chain H (length=37) [
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ggataacttcgtatagcatacattatacgaagttatc
Receptor-Ligand Complex Structure
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PDB
1q3v
Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Resolution
2.91 Å
Binding residue
(original residue number in PDB)
M44 S47 R50 R81 A84 K86 T87 K132 R159 R173 T202 R241 V242 K244 L256 S257 R259 R282 W315 I320 Y324
Binding residue
(residue number reindexed from 1)
M24 S27 R30 R61 A64 K66 T67 K112 R139 R153 T182 R221 V222 K224 L236 S237 R239 R262 W295 I300 Y304
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
Biological Process
GO:0006310
DNA recombination
GO:0015074
DNA integration
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Molecular Function
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Biological Process
External links
PDB
RCSB:1q3v
,
PDBe:1q3v
,
PDBj:1q3v
PDBsum
1q3v
PubMed
12954782
UniProt
P06956
|RECR_BPP1 Recombinase cre (Gene Name=cre)
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