Structure of PDB 1pek Chain E Binding Site BS02

Receptor Information
>1pek Chain E (length=279) Species: 37998 (Parengyodontium album) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVVKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1pek Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		H69 N161 I220 S221 G222 S224
Binding residue
(residue number reindexed from 1)		H69 N161 I220 S221 G222 S224
Enzymatic activity
Catalytic site (original residue number in PDB) S224
Catalytic site (residue number reindexed from 1) S224
Enzyme Commision number 3.4.21.64: peptidase K.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1pek, PDBe:1pek, PDBj:1pek
PDBsum1pek
PubMed8340410
UniProtP06873|PRTK_PARAQ Proteinase K (Gene Name=PROK)

[Back to BioLiP]