Structure of PDB 1nzb Chain E Binding Site BS02

Receptor Information
>1nzb Chain E (length=321) Species: 10678 (Punavirus P1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DEVRKNLMDMFRDRQAFSEHTWKMLLSVCRSWAAWCKLNNRKWFPAEPED
VRDYLLYLQARGLAVKTIQQHLGQLNMLHRRSGLPRPSDSNAVSLVMRRI
RKENVDAGERAKQALAFERTDFDQVRSLMENSDRCQDIRNLAFLGIAYNT
LLRIAEIARIRVKDISRTDGGRMLIHIGRTKTLVSTAGVEKALSLGVTKL
VERWISVSGVADDPNNYLFCRVRKNGVAAPSATSQLSTRALEGIFEATHR
LIYGAKDDSGQRYLAWSGHSARVGAARDMARAGVSIPEIMQAGGWTNVNI
VMNYIRNLDSETGAMVRLLED
Ligand information
Receptor-Ligand Complex Structure
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PDB1nzb Crystal structure of a wild-type Cre recombinase-loxP synapse reveals a novel spacer conformation suggesting an alternative mechanism for DNA cleavage activation
Resolution3.1 Å
Binding residue
(original residue number in PDB)		K43 M44 S47 R50 R81 L83 A84 K86 T87 A131 K132 R159 R173 T202 L203 R241 V242 K244 S257 R259 R282 Y283 W315 I320 Y324
Binding residue
(residue number reindexed from 1)		K23 M24 S27 R30 R61 L63 A64 K66 T67 A111 K112 R139 R153 T182 L183 R221 V222 K224 S237 R239 R262 Y263 W295 I300 Y304
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006310 DNA recombination
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:1nzb, PDBe:1nzb, PDBj:1nzb
PDBsum1nzb
PubMed12954782
UniProtP06956|RECR_BPP1 Recombinase cre (Gene Name=cre)

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