Structure of PDB 1lq8 Chain E Binding Site BS02

Receptor Information
>1lq8 Chain E (length=329) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEG
LGLNLQKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDT
FVSAMKTLYLADTFPTNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSN
AVVIMVNYIFFKAKWETSFNHKGTQEQDFYVTSETVVRVPMMSREDQYHY
LLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEKTLRKWLKMF
KKRQLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSNIQV
SEMVHKAVVEVDESGTRAAAATGTIFTFR
Ligand information
>1lq8 Chain H (length=29) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NSQRLVFNRPFLMFIVDNNILFLGKVNRP
Receptor-Ligand Complex Structure
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PDB1lq8 Crystal Structure of Protein C Inhibitor Provides Insights into Hormone Binding and Heparin Activation
Resolution2.4 Å
Binding residue
(original residue number in PDB)
L122 D124 V127 S128
Binding residue
(residue number reindexed from 1)
L97 D99 V102 S103
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004867 serine-type endopeptidase inhibitor activity
Cellular Component
GO:0005615 extracellular space

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Molecular Function

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Cellular Component
External links
PDB RCSB:1lq8, PDBe:1lq8, PDBj:1lq8
PDBsum1lq8
PubMed12575940
UniProtP05154|IPSP_HUMAN Plasma serine protease inhibitor (Gene Name=SERPINA5)

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