Structure of PDB 1bjr Chain E Binding Site BS02

Receptor Information

>1bjr Chain E (length=279) Species: 37998 (Parengyodontium album) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

AAQTNAPWGLARISSTSPGTSTYYYDESAGQGSCVYVIDTGIEASHPEFE
GRAQMVKTYYYSSRDGNGHGTHCAGTVGSRTYGVAKKTQLFGVKVLDDNG
SGQYSTIIAGMDFVASDKNNRNCPKGVVASLSLGGGYSSSVNSAAARLQS
SGVMVAVAAGNNNADARNYSPASEPSVCTVGASDRYDRRSSFSNYGSVLD
IFGPGTSILSTWIGGSTRSISGTSMATPHVAGLAAYLMTLGKTTAASACR
YIADTANKGDLSNIPFGTVNLLAYNNYQA

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1bjr Chain E Residue 290 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1bjr Crystal structure of a complex formed between proteolytically-generated lactoferrin fragment and proteinase K.
Resolution	2.44 Å
Binding residue (original residue number in PDB)	R12 N257 L272 A273 Y274
Binding residue (residue number reindexed from 1)	R12 N257 L272 A273 Y274
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	S224
Catalytic site (residue number reindexed from 1)	S224
Enzyme Commision number	3.4.21.64: peptidase K.

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity
GO:0008236	serine-type peptidase activity

	Biological Process
GO:0006508	proteolysis

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Molecular Function

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Biological Process

External links

PDB	RCSB:1bjr, PDBe:1bjr, PDBj:1bjr
PDBsum	1bjr
PubMed	9741842
UniProt	P06873\|PRTK_PARAQ Proteinase K (Gene Name=PROK)

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