Structure of PDB 1vy4 Chain DZ Binding Site BS02

Receptor Information

>1vy4 Chain DZ (length=174) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MEYRLKAYYREGEKPSALRRAGKLPGVMYNRHLNRKVYVDLVEFDKVFRQ
ASIHHVIVLELPDGQSLPTLVRQVNLDKRRRRPEHVDFFVLSDEPVEMYV
PLRFVGTPAGVRAGGVLQEIHRDILVKVSPRNIPEFIEVDVSGLEIGDSL
HASDLKLPPGVELAVSPEETIAAV

Ligand information

>1vy4 Chain DB (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga

.<<<<<<<<<.....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>..>>>>>>>>>.

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1vy4 A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome.
Resolution	2.6 Å
Binding residue (original residue number in PDB)	R10 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87 F89
Binding residue (residue number reindexed from 1)	R10 R19 Y29 N30 R31 N34 R72 Q73 R79 E84 H85 D87 F89

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0008097	5S rRNA binding
GO:0019843	rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

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Cellular Component

External links

PDB	RCSB:1vy4, PDBe:1vy4, PDBj:1vy4
PDBsum	1vy4
PubMed	25132179
UniProt	Q5SHZ1\|RL25_THET8 Large ribosomal subunit protein bL25 (Gene Name=rplY)

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