Structure of PDB 4w2g Chain DQ Binding Site BS02 |
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>4w2g Chain DA (length=2800)
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agaugguaagggcccacgguggaugccucggcacccgagccgaugaagga cguggcuaccugcgauaagccagggggagccgguagcgggcguggauccc uggauguccgaaugggggaacccggccggcgggaacgccggucaccgcgc ugcgcggggggaaccuggggaacugaaacaucucaguacccagaggagag gaaagagaaaucgacucccugaguagcggcgagcgaaaggggaccagccu aaaccguccggcuuguccgggcggggucguggggcccucggacaccgaau ccccagccuagccgaagcuguugggaagcagcgccagagagggugaaagc cccguaggcgaaagguggggggauaggugaggguacccgaguaccccgug guucguggagccaugggggaaucugggcggaccaccgccuaaggcuaagu acuccgggugaccgauagcgcaccaguaccgugagggaaaggugaaaaga accccgggaggggagugaaauagagccugaaaccgugggcuuacaagcag ucacggccccggggguuguggcgugccuauugaagcaugagccggcgacu cacggucgugggcgagcuuaagccguugaggcggaggcguagggaaaccg aguccgaacagggcgcaagcgcgcaaaguccgcggccguggacccgaaac cgggcgagcuagcccuggccagggugaagcuggggugagacccaguggag gcccgaaccggugggggaugcaaaccccucggaugagcuggggcuaggag ugaaaagcuaaccgagcccggagauagcugguucuccccgaaaugacuuu agggucagccucaggcgcugacuggggccuguagagcacugauagggcua gggggcccaccagccuaccaaacccugucaaacuccgaagggucccaggu ggagccugggagugagggcgcgagcgauaacguccgcguccgagcgcggg aacaaccgagaccgccagcuaaggcccccaagucugggcuaagugguaaa ggauguggcgccgcguggcgccgcgccgaaaaugaucggggcuuaagccc agcgccgaagcugcgggucuggggccccaggcgguaggggagcguucccg augccgaugaaggccgacccgcgagggcggcuggagguaagggaagugcg aaugccggcaugaguaacgauaaagagggugagaaucccucucgccguaa gcccaaggguuccuacgcaauggucgucagcguaggguuaggcgggaccu aaggugaagccgaaaggcguagccgaagggcagccgguuaauauuccggc ccuucccgcaggugcgauggggggacgcucuaggcuagggggaccggagc cauggacgagcccggccagaagcgcagggugggagguaggcaaauccgcc ucccaacaagcucugcgugguggggaagcccgcgggugacaaccccccga agccagggagccaagaaaagccucuaagcacaaccugcgggaacccguac cgcaaaccgacacaggugggcgggugcaagagcacucaggcgcgcgggag aacccucgccaaggaacucugcaaguuggccccguaacuucgggagaagg ggugcucccuggggugaugagccccggggagccgcagugaacaggcucug gcgacuguuuaccaaaaacacagcucucugcgaacucguaagaggaggua uagggagcgacgcuugcccggugccggaaggucaaggggaggggugcaag ccccgaaccgaagccccggugaacggcggccguaacuauaacgguccuaa gguagcgaaauuccuugucggguaaguuccgaccugcacgaaaagcguaa cgaccggagcgcugucucggcgagggacccggugaaauugaacuggccgu gaagaugcggccuacccguggcaggacgaaaagaccccguggagcuuuac ugcagccugguguuggcucuuggucgcgccugcguaggauaggugggagc cugugaacccccgccuccgggugggggggaggcgccggugaaauaccacc cuggcgcggcugggggccuaacccucggauggggggacagcgcuuggcgg gcaguuugacuggggcggucgccuccuaaaagguaacggaggcgcccaaa gguccccucaggcgggacggaaauccgccggagagcgcaaggguagaagg gggccugacugcgaggccugcaagccgagcaggggcgaaagccgggccua gugaaccgguggucccguguggaagggccaucgaucaacggauaaaaguu accccggggauaacaggcugaucucccccgagcguccacagcggcgggga gguuuggcaccucgaugucggcucgucgcauccuggggcugaagaagguc ccaaggguugggcuguucgcccauuaaagcggcacgcgagcuggguucag aacgucgugagacaguucggucucuauccgccacgggcgcaggaggcuug aggggggcucuuccuaguacgagaggaccggaagggacgcaccucugguu ucccagcugucccuccaggggcauaagcuggguagccaugugcggaaggg auaaccgcugaaagcaucuaagcgggaagcccgccccaagaugaggccuc ccggcagccgguaaggacccgggaagaccacccgguggaugggccggggg uguaagcgccgcgaggcguugagccgaccggucccaaucguccgaggucu |
<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<......<<< <<<.((..((.>>>.....<<<<<<<..<<<))..)).>>>.....>>>> >>>...>>>....<<<....>>><<<<<<<<....>>>>>>>>.<<<<<< .>>>>>>.>>...<<<<<<.....<......>......>>>>>.>..... ....<<....>>...<<<<<.....<<.....>>....>>>>>...<<<. ...<<<<<<<<.....>>>>>>>>......<<<<<<<<<....<<<...< <<<<.<<<<.<<<...<<<<<......>>>>>((......<<<.....)) >>>...>>>...>>>>..>>>>>..>>>>>>>>>.>>>.....<<<<<<< <<.......>>>>>>>>>......<<<<<..((((>>>>>..>>>..... .>>.>>>>>>.>>...............<<....>>....>>........ .<<<<....>>>>..................>>>>>>>>>>>.......< <<<<<<<<<<.>>>>>>>>>>>...<............>.<<<<<<.... <<<<<<<<<<<<<..<<<...<<<.....>>>...>>>...<<....>>. .<<<<.....>>>>....<<..>>...>>>>>>>>>>>>>..<<.<...< <<<<<....<<<<<<<<<<..<<<....<<<<<<......>>>>>>.... .>>>...<<<..<<<<........>>>>.>>>....>>>>>>>>>>..<< <.....>>>......>>>>>>......>.>>..<<<<<<....<<<<<.. ..>>>>><<<<<<<<<.....<<<<<<<<<...<<<...<<<<<<<<... .<<<<<......>>>>.>....>>>>>>>>..>>.>...>>>>>>>>>.. ...>>>>>>>.>>..<<<<<<<.<<......>>.>>>>>>>.....<<<. .....>>>...<<<<.<<<...<<<(((.....<<<<<<........... <<..<<<<<<<<<..>>>>>>>>>.>>..........)))......>>>> >>.>>>...>>>>>>><<<<<<<<>>>>>>>>....>>>>>>..<<<<<. ..<<<......<<<<<.<<<....>>>>>>>>...>>>..>>>>>..... ...>>>>>><......<<.....<<<<<<.......>>>>>><<<<.... <<<<<.<<...<<<<<<...<<.....>>.>>>>>>....((<<<<.<<. ..<<<...<<<....>>>...>>>...>>...<<<<<........>>>>> ))<<<<<<<<<<<<<...<<<<....<<<<<.<<<..<<<<<.<<<<.<< ..[[[[...>>>>>><<<...<<<<<<<<<<<<<<<<.<<.....>>>>> >>>>.....>>>>>>>>>..>>><...<<<<..>>>>.....>>>>>>.. .>>>..>>>>>.........>>>>...>>...>>>>>>>>>>>>>>>..> >.....<<......>>>>>>>.<<<<<....>>>>>..>>>>..<<<<.. ..<<<<<<<<.<<.........<.....<<<<<.....<..>......>> >>><<<<<<<<<<<<.....>>>>>>>>>>>>............<<<<<< <<<..<<<.........>>>..<<<<<<<.....<<<....>>>...... .>>>>>>>.<<<<<.<<<..<<<<<<<..<<<...<<...<<<<<....> >>>>...>>...>>>>>>>>..>>>>><<<<<<.......>>>>>>.... ....<...........<<<<<<.....>>>>>>.....>....>>>>>.. >>.>>>>>>>..>..>>.>>>>>>>>.>>>>>>.....>.....<<<<<. .......>>>>>..<<<<<<<<.<<<.........<<<<.<<<<<<..<< <<<.<<<.<<<<<.<<<<<<<<<<<<<<<<...........<<<<<..<< <......<<<<<.<<....>>.>>>>>...>>>............>>>>> ..>>>>>>>>>>>>>>>>...<<<<<....>>>>>....>>>>>.>>>.. >>>>>..<<<<.....>>>><<<<<<...........>>>>>>..<<... <<<<<<<...<<<<<<.......>>>>>>.....<<...(((>>....>> >>>>>...<<<<..<<<......>>>..>>>>.<<<....>>>.>>))). ......<<<<<<<.<<..))))..>>>>>>>>>.............>>>> ..>>>>>>.......<<<<.<.<<<<<<...<<.......>>...>>>>> >...>>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......>>>> >>>..>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>....< <<<<<<....>>>.>>>>........>>>>>>>>>>>....<<<<<<<.. .<<<<..<<<<<<<...............>>>>>>>.<<<<<...<<<<. ..<<<<<<<<<<<]]]]>>>>>>...>>>>>...>>>>.>>>>>...<<< ....<<<<<...........>>>>>....>>>.>>>>.......>>>>>> >.<<<.>>>.....<<<<<<<<<.......>>>>>....<<<<<<<<.<< <....<<<<<....>>>>>...>>>..>>>>>.>>>...>>>>....>>> |
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PDB | 4w2g Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. |
Resolution | 2.55 Å |
Binding residue (original residue number in PDB) | P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K22 G23 G24 Y26 F29 A40 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 R101 H123 K124 P126 K128 |
Binding residue (residue number reindexed from 1) | P4 R5 R6 K8 Y9 K11 Q12 Q13 R14 G15 R16 L17 K22 G23 G24 Y26 F29 A40 W41 Q46 A49 R56 K63 R67 F69 D71 Y74 K76 K77 E80 V81 R82 M83 G84 K85 G86 K87 R101 H123 K124 P126 K128 |
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Enzyme Commision number |
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