Structure of PDB 6hhq Chain DC Binding Site BS02

Receptor Information
>6hhq Chain DC (length=148) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PSRFTKTRKHRGHVSAGKGRIGKHRKHPGGRGMAGGQHHHRINMDKYHPG
YFGKVGMRYFHKQQAHFWKPVLNLDKLWTLIPEDKRDQYLKSASKETAPV
IDTLAAGYGKILGKGRIPNVPVIVKARFVSKLAEEKIRAAGGVVELIA
Ligand information
Ligand IDOHX
InChIInChI=1S/6H2N.Os/h6*1H2;/q6*-1;+6
InChIKeyOWCQTVJQFLTQTE-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01
CACTVS 3.370
OpenEye OEToolkits 1.7.0		N[Os](N)(N)(N)(N)N
FormulaH12 N6 Os
Nameosmium (III) hexammine;
osmium(6+) hexaazanide
ChEMBL
DrugBank
ZINC
PDB chain6hhq Chain AR Residue 3510 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6hhq Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		G23 K24
Binding residue
(residue number reindexed from 1)		G22 K23
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0043232 intracellular non-membrane-bounded organelle
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6hhq, PDBe:6hhq, PDBj:6hhq
PDBsum6hhq
PubMed30759226
UniProtP02406|RL28_YEAST Large ribosomal subunit protein uL15 (Gene Name=RPL28)

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