Structure of PDB 9f1b Chain DB Binding Site BS02

Receptor Information

>9f1b Chain DB (length=837) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGL
TLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYR
NALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGY
AIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAG
LYREALEHLCTYEKQICDKLAVEETKGELLLQLCRLEDAADVYRGLQERN
PENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGE
KFKECLDKFLRMNFSKGCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLK
SCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTAIEST
PTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLK
ANLIKEAEEMCSKFTREGTSAVENLNEMQCMWFQTECAQAYKAMNKFGEA
LKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFY
FKAARIAIEIYLKLHDNPLTDENKEHEADTANMSDKELKKLRNKQRRAQK
KAQIEEEKKNAEKEKQQRNQKKKKDDDDEEIGGPKEELIPEKLAKVETPL
EEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSS
HPWLHECMIRLFNTAVCESKDLSDTVRTVLKQEMNRLFGATNPKNFNETF
LKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTLDESLTNRNLQTCME
VLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMPP

Ligand information

Ligand ID

IHP

InChI

InChI=1S/C6H18O24P6/c7-31(8,9)25-1-2(26-32(10,11)12)4(28-34(16,17)18)6(30-36(22,23)24)5(29-35(19,20)21)3(1)27-33(13,14)15/h1-6H,(H2,7,8,9)(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)(H2,19,20,21)(H2,22,23,24)/t1-,2-,3-,4+,5-,6-

InChIKey

IMQLKJBTEOYOSI-GPIVLXJGSA-N

SMILES

Software	SMILES
CACTVS 3.385	O[P](O)(=O)O[CH]1[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH](O[P](O)(O)=O)[CH]1O[P](O)(O)=O
ACDLabs 12.01 OpenEye OEToolkits 2.0.7	C1(C(C(C(C(C1OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O
CACTVS 3.385	O[P](O)(=O)O[C@@H]1[C@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@@H](O[P](O)(O)=O)[C@H](O[P](O)(O)=O)[C@H]1O[P](O)(O)=O

Formula

C6 H18 O24 P6

Name

INOSITOL HEXAKISPHOSPHATE;
MYO-INOSITOL HEXAKISPHOSPHATE;
INOSITOL 1,2,3,4,5,6-HEXAKISPHOSPHATE

PDB chain

9f1b Chain DB Residue 901 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	9f1b NAC guides a ribosomal multienzyme complex for nascent protein processing.
Resolution	3.01 Å
Binding residue (original residue number in PDB)	W486 K556
Binding residue (residue number reindexed from 1)	W482 K552
Annotation score	4

External links

PDB	RCSB:9f1b, PDBe:9f1b, PDBj:9f1b
PDBsum	9f1b
PubMed	39169182
UniProt	Q9BXJ9\|NAA15_HUMAN N-alpha-acetyltransferase 15, NatA auxiliary subunit (Gene Name=NAA15)

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