Structure of PDB 6hcf Chain D3 Binding Site BS02

Receptor Information
>6hcf Chain D3 (length=293) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVKVVKNKAYFKRYQVKFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMI
VRVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAAAYCTG
LLLARRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGAFTCYLDAGLAR
TTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQ
NVADYMRYLMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPV
YEKKPKREVKKKRWNRPKMSLAQKKDRVAQKKASFLRAQERAA
Ligand information
>6hcf Chain 72 (length=120) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gucuacggccauaccacccugaacgcgcccgaucucgucugaucucggaa
gcuaagcagggucgggccugguuaguacuuggaugggagaccgccuggga
auaccgggugcuguaggcuu
....<.<<.....<<<<<<<<.....<<<<<..............>>>..
>>....>>>>>>.>><<<<<<<......<.<<..<<....>>.>>.>...
..>>>>>>>.>>.>......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6hcf ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Resolution3.9 Å
Binding residue
(original residue number in PDB)		K10 F13 Y16 V18 F20 R21 R22 R24 R33 V37 R50 I52 R54 N57 R58 A67 R68 G71 D72 I74 N94 Y95 R152 K158 Y207 Q222 S224 Q225 Y226 Y253 K255 K256 R259 V261 W266 N267 K270 M271 L273 K276 R279
Binding residue
(residue number reindexed from 1)		K8 F11 Y14 V16 F18 R19 R20 R22 R31 V35 R48 I50 R52 N55 R56 A65 R66 G69 D70 I72 N92 Y93 R150 K156 Y205 Q220 S222 Q223 Y224 Y251 K253 K254 R257 V259 W264 N265 K268 M269 L271 K274 R277
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008097 5S rRNA binding
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0006412 translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6hcf, PDBe:6hcf, PDBj:6hcf
PDBsum6hcf
PubMed30293783
UniProtP19949|RL5_RABIT Large ribosomal subunit protein uL18 (Gene Name=RPL5)

[Back to BioLiP]