Structure of PDB 8thb Chain D Binding Site BS02

Receptor Information
>8thb Chain D (length=332) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LAQQPWVEKYRPKNLDEVTAQDHAVTVLKKTLKSANLPHMLFYGPPGTGK
TSTILALTKELYGPDLMKSRILELNASDERGISIVREKVKNFARLTVSKP
SKHDLENYPCPPYKIIILDEADSMTADAQSALRRTMETYSGVTRFCLICN
YVTRIIDPLASRCSKFRFKALDASNAIDRLRFISEQENVKCDDGVLERIL
DISAGDLRRGITLLQSASKGAQYLGDGKNITSTQVEELAGVVPHDILIEI
VEKVKSGDFDEIKKYVNTFMKSGWSAASVVNQLHEYYITNDNFDTNFKNQ
ISWLLFTTDSRLNNGTNEHIQLLNLLVKISQL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain8thb Chain D Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8thb Structure of the PCNA unloader Elg1-RFC
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T72 D140
Binding residue
(residue number reindexed from 1)		T51 D119
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
Biological Process
GO:0000076 DNA replication checkpoint signaling
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8thb, PDBe:8thb, PDBj:8thb
PDBsum8thb
PubMed38427736
UniProtP40348|RFC2_YEAST Replication factor C subunit 2 (Gene Name=RFC2)

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