Structure of PDB 8ssr Chain D Binding Site BS02

Receptor Information
>8ssr Chain D (length=230) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KPFKCSMCDYASVEVSKLKRHIRSHTGERPFQCSLCSYASRDTYKLKRHM
RTHSGEKPYECYICHARFTQSGTMKMHILQKHTENVAKFHCPHCDTVIAR
KSDLGVHLRKQHSYIEQGKKCRYCDAVFHERYALIQHQKSHKNEKRFKCD
QCDYACRQERHMIMHKRTHTGEKPYACSHCDKTFRQKQLLDMHFKRYHDP
NFVPAAFVCSKCGKTFTRRNTMARHADNCA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8ssr Structures of CTCF-DNA complexes including all 11 zinc fingers.
Resolution3.14 Å
Binding residue
(original residue number in PDB)
Y386 R389 K393 R396 H397 T400 K405 Q418 K429 R448 D451 H455 Q459 R479 Y502 K530 F532 Q536 L537 M540 R544 R566
Binding residue
(residue number reindexed from 1)
Y38 R41 K45 R48 H49 T52 K57 Q70 K81 R100 D103 H107 Q111 R131 Y154 K182 F184 Q188 L189 M192 R196 R218
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:8ssr, PDBe:8ssr, PDBj:8ssr
PDBsum8ssr
PubMed37439339
UniProtP49711|CTCF_HUMAN Transcriptional repressor CTCF (Gene Name=CTCF)

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