Structure of PDB 8sfk Chain D Binding Site BS02

Receptor Information

>8sfk Chain D (length=314) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRIPLVGKDSIESKDIGFTLIHEHLRVFSEAVRQQWPHLYNEDEEFRNAV
NEVKRAMQFGVKTIVDPTVMGLGRDIRFMEKVVKATGINLVAGTGILIYI
DLPFYFLNRSIDEIADLFIHDIKEGIQGTLNKAGFVKIAADEPGITKDVE
KVIKAAAIANKETKVPIITHSNAHNNTGLEQQRILTEEGVDPGKILIGHL
GDTDNIDYIKKIADKGSFIGLDRYGLDMFLPVDKRNETTLRLIKDGYSDK
IMISHDYCCTIDMGTAKPEYKPKLAPRWSTTLIFEDTIPFLKRNGVNEEV
IATIFKENPKKFFS

Ligand information

Ligand ID

InChI

InChI=1S/Co/q+2

InChIKey

XLJKHNWPARRRJB-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Co+2]
CACTVS 3.341	[Co++]

Formula

Name

COBALT (II) ION

PDB chain

8sfk Chain D Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	8sfk Changes in Active Site Loops Conformation Relates to a Transition from Lactonase to Phosphotriesterase
Resolution	1.4 Å
Binding residue (original residue number in PDB)	K137 H170 H199
Binding residue (residue number reindexed from 1)	K137 H170 H199
Annotation score	1

Enzymatic activity

Enzyme Commision number

3.1.8.1: aryldialkylphosphatase.

Gene Ontology

	Molecular Function
GO:0004063	aryldialkylphosphatase activity
GO:0008270	zinc ion binding
GO:0016787	hydrolase activity
GO:0016788	hydrolase activity, acting on ester bonds
GO:0046872	metal ion binding

	Biological Process
GO:0009056	catabolic process

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Molecular Function

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Biological Process

External links

PDB	RCSB:8sfk, PDBe:8sfk, PDBj:8sfk
PDBsum	8sfk
PubMed
UniProt	Q97VT7\|PHP_SACS2 Aryldialkylphosphatase (Gene Name=php)

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