Structure of PDB 8jkq Chain D Binding Site BS02

Receptor Information
>8jkq Chain D (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NGKLRQWLIDQIDSGKYPLVWENEEKSIFRIPWKHAGKQDYNREEDAALF
KAWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDP
YKVYRIVP
Ligand information
Receptor-Ligand Complex Structure
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PDB8jkq Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Resolution3.09 Å
Binding residue
(original residue number in PDB)		G22 L24 W74 K78 K80 R95 R96 K103
Binding residue
(residue number reindexed from 1)		G2 L4 W53 K57 K59 R74 R75 K82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jkq, PDBe:8jkq, PDBj:8jkq
PDBsum8jkq
PubMed37683642
UniProtF2Z3D5

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