Structure of PDB 8jko Chain D Binding Site BS02

Receptor Information
>8jko Chain D (length=108) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQYNREEDAALFK
AWALFKGKFREGIDKPDPPTWKRRLRCALNKSNDFEELVERSQLDISDPY
KVYRIVPE
Ligand information
Receptor-Ligand Complex Structure
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PDB8jko Molecular basis for the functional roles of the multimorphic T95R mutation of IRF4 causing human autosomal dominant combined immunodeficiency.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		G22 L24 H56 G58 K59 W74 K78 R96 K103
Binding residue
(residue number reindexed from 1)		G1 L3 H35 G37 K38 W52 K56 R74 K81
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8jko, PDBe:8jko, PDBj:8jko
PDBsum8jko
PubMed37683642
UniProtF2Z3D5

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