Structure of PDB 8i24 Chain D Binding Site BS02

Receptor Information
>8i24 Chain D (length=1152) Species: 637887 (Acetivibrio thermocellus DSM 1313) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NNFDSIRIGLASPEKIREWSRGEVKKPETINYRTLKPERDGLFCERIFGP
QKDWECHCGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVSHI
WYFKGIPSRMGLLLDMSPRALEKILYFAAYVVIDPGQTPLSKKQILSEKE
YRDSLEKFGPKFRAGMGAEAVRELLQEINLDELSAELREEIKQSTGQKRV
RAIKRLEVVEAFRQSQNKPEWMILDVIPVIPPELRPMVQLDGGRFATSDL
NDLYRRVINRNNRLKRLLDLGAPDIIVRNEKRMLQEAVDALIDNGRRGRP
VTGPGNRPLKSLSDMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKIYQ
CGLPKEMALELFKPFVMKKLVNDGLAHNIKSAKRMVERVRNEVWDVLEEV
IKEHPVLLNRAPTLHRLGIQAFEPVLVEGRALKLHPLVCTAYNADFDGDQ
MAIHVPLSAEAQAEARFLMLSANNLLKPQDGKPVAVPTQDMVLGSYYLTI
LKEGAKGEGRVFTSMDEAVMAYDNGEIELHSKIKVRMKRVVDGVEKSKII
ETTLGRLIFNEAIPQDLGFVDRSDPDKIFDLEVDFLVGKNELKKIIDKSI
KVHGTTKTAILLDKIKELGFKYSTKGAITISISDMVIPEVKAKYIKETEE
KIEKITKQYKRGLISDEERYNSVIAAWTEASENITRALINNLDRFNPVYM
MSQSGARGNINQIKQLAGMRGLMADTSGKTIEFPIKANFREGLTVMEFFI
STHGARKGLADTALRTADSGYLTRRLVDVSQDVIVRETDCGTRKGIEVTD
IKDGNEVIEELSERIIGRYPVGNIVHPETGEIIVEAGRMITDQDAEKIVK
AGIKKVRIRSVLTCHSEYGVCAKCYGANLATGEECNVGEAVGIIAAQSIG
EPGTQLTMRTGEDITQGLPRVEELFEARKPKGLAIISEIKGTVKISETKK
KREIVVTSEDGETRSYLIPYGSRIKVSDGDQVEAGDELTEGSVNPHDILK
IKGVEAVQTYLVHEVQKVYRMQGVDINDKHIEVIVRQMLRKVKVEDPGDT
SLLPGGLVDVFDFEEENAKAIAEGKKPAVAKRALLGITKAALATDSFLSA
ASFQETTRVLTEAAIKGKVDPLVGLKENVIIGKLIPAGTGMSRYKDITIS
TV
Ligand information
>8i24 Chain P (length=52) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aatttcaccccttatagatagacgtataccggaatggttttatgtcgcat
tg
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8i24 Structure of the transcription open complex of distinct sigmaI factors
Resolution3.36 Å
Binding residue
(original residue number in PDB)		I133 R323 R351 T793 A794 Y798 Q1138 E1139
Binding residue
(residue number reindexed from 1)		I106 R296 R324 T766 A767 Y771 Q1104 E1105
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0008270 zinc ion binding
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8i24, PDBe:8i24, PDBj:8i24
PDBsum8i24
PubMed37833284
UniProtA3DIZ5|RPOC_ACET2 DNA-directed RNA polymerase subunit beta' (Gene Name=rpoC)

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